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Beilstein J. Org. Chem. 2019, 15, 2644–2654, doi:10.3762/bjoc.15.257
Graphical Abstract
Figure 1: The 2,1,3-benzothiadiazole (BTD) core and its derivatives that are successfully applied in bioimagi...
Scheme 1: Synthesis of the plasma membrane BTD probe (BTD-4APTEG) and its structural features.
Figure 2: (Left) UV–vis, (center) fluorescence emission and (right) solvatochromic effect (Stokes shift in wa...
Figure 3: Mean absolute error (MAE) comparing both the experimental and the estimated TD-DFT λmax positions i...
Figure 4: (A) CAM-B3LYP/6-311+G(d) optimized geometry of BTD-4APTEG (implicit DMSO). (B) TD-DFT UV–vis spectr...
Figure 5: Cellular viability determined by MTT analysis after 24 h treatment with the developed dye BTD-4APTE...
Figure 6: MCF-7 cells incubated with BTD-4APTEG (1 μM) in live (A) and (B) and fixed cells (C) and (D). (A) a...
Figure 7: Co-staining experiments using the commercially available CellMask (red emission) and BTD-4APTEG (gr...